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Confocal microscopy is an imaging technique widely used for increasing cellular spatial resolution by eliminating out of focus light through the use of pinholes placed at the confocal plane of the lens. Confocal microscopy has become an essential tool for the life sciences and is the technique of choice for high resolution microscopy.


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Samantha Peel Senior Research Scientist, Discovery Sciences 英雄联盟竞猜平台

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The use of 更多 physiological, cellular and tissue models including primary cells, stem cells and multicellular systems in preclinical drug discovery is now common place. Such models are often 3D in nature and therefore cannot be effectively imaged by traditional widefield systems. In addition, AstraZeneca has invested heavily in phenotypic screening initiatives and precise genome editing. Having access to powerful detection microscopes that can detect subtle cellular phenotypic changes is critical to realising the full potential of such investments.

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We evaluated current and future project demand and it was clear that there were many projects spanning our R&D functions that could benefit from the purchase of the CV7000. This instrument promises new capability with improved assay quality at fast acquisition rates and will enable Discovery Sciences to expand their assay 文件夹 to support all of the IMED Biotech Unit. The ability to image and extract data from 更多 complex cellular models with improved physiological relevance early in drug discovery will speed up the discovery process and reduce attrition.

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The microscope was installed at the latter end of 2015 and we have already started to use the system to impact projects where cellular spatial resolution is a requirement and for use with thicker tissue specimens.

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We are open to collaboration and would encourage interested parties to get in touch if they are interested in getting access to our microscopes.

Confocal microscopy has become an essential tool for the life sciences and is the technique of choice for high resolution microscopy.

Samantha Peel



英雄联盟竞猜平台

The best science doesn't happen in isolation.

We partner with others around the world, combining the great science in our labs with complementary technologies, know-how and molecules to accelerate the delivery of new life-changing medicines.


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and help us deliver life-changing medicines. Be among our employees who continue to make us an innovation-driven company that stands firmly among the world’s leaders in biopharmaceuticals.